PREVALENSI TIKUS TERINFEKSI Leptospira interogans DI KOTA SEMARANG, JAWA TENGAH

Ristiyanto Ristiyanto, Tri Wibawa, Setyawan Budiharta, Supargiono Supargiono

Abstract


Abstrak

Leptospirosis merupakan zoonosis.Penyakit ini sering dijumpai di daerah perkotaan terutama yang sering dilanda banjir.Manusia terinfeksi bakteri Leptospira melalui air atau tanah yang terkontaminasi dengan urin atau cairan tubuh inang reservoir.Tikus adalah inang reservoir leptospirosis.Penelitian ini bertujuan untuk mengetahui populasi tikus yang terinfeksi Leptospira dan interaksi antara pasien suspek leptospira dengan tikus­Kota­Semarang,­Jawa­Tengah.­Selain­itu­dilakukan­pula­identifikasi­serovar­Leptospira­padatikus­diKota Semarang, Jawa Tengah. Jenis penelitian adalah potonglintang (cross sectional).Dilakukan pengamatan di rumah dan lingkungan tempat tinggal 68 kasus leptospirosis. Penangkapan tikus menggunakan perangkap hidup sejumlah 100 buah.Pemasang perangkap di dalam dan di luar rumah selama 3 hari.  Tikus yang tertangkap­diidentifikasi­dan­diambil­serum­darahnya­untuk­mengetahui­serovar­Leptospira­dengan­uji­MAT.Seluruh 68 kasus leptospirosis dari Rumah Sakit di Kota Semarang memiliki riwayat interaksi dengan tikus. Prevalensi tikus terinfeksi bakteri leptospira  untuk tikus got (R. norvegicus) 33,43% dan tikus rumah (R. tanezumi)­13,69%.­Serovar­Leptospira­yang­diidentifikasi­pada­tikus­got­(R.­norvegicus)­adalah­Djasiman(40,55% dari 27 ekor), Icterohaemorhagie (22,22% ), Autumnalis (20,35) dan Bataviae (16,68%). Sementara pada­tikus­rumah­(R.­tanezumi)­dapat­diidentifikasikan­serovar­Autumnalis­(66,67%­dari­3­ekor)­dan­Bataviae(33,33%). Hal ini menunjukkan bahwa tikus merupakan reservoir penting dari leptospirosis. Penelitian ini menunjukkan bahwa tikus got (R. norvegicus) dan tikus rumah (R. tanezumi) memiliki potensi besar untuk menjadi vektor penularan bakteri Leptospira di Kota Semarang.

Kata Kunci : Leptospirosis, Tikus, Faktor Risiko, Semarang

Abstract

Leptospirosis­is­a­zoonosis.­The­disease­is­often­found­in­urban­areas,­especially­the­frequent­flooding.­Humansinfected­with­Leptospira­bacteria­through­water­or­soil­contaminated­with­urine­or­body­fluids­of­the­hostreservoir. Rats are the reservoir host of leptospirosis. This study aims to determine the population of mice infected with Leptospira and interactions between patients with suspected leptospirosis with rats Semarang, Central­Java.­In­addition­it­also­conducted­in­mice­Leptospira­serovar­identification­in­Semarang,­CentralJava. This type of research is potonglintang (cross­sectional). Observation at home and living environment 68 cases of leptospirosis.Catching mice using live traps some 100 pieces.Trapper inside and outside the house for­3­days.­Mice­that­were­caught­were­identified­and­taken­to­determine­blood­serum­test­leptospira­serovarMAT. The whole 68 cases of leptospirosis Hospital in Semarang has a history of interaction with the rats. 86Vektora Volume 7 Nomor 2, Oktober 2015: 85 - 92Prevalence of mice infected with the bacteria leptospira for sewer rat (R. norvegicus) 33.43% and the house mouse (R. tanezumi)­13.69%.­Leptospira­serovar­identified­in­rats­(R. norvegicus) is Djasiman (40.55% of 27 animals), Icterohaemorhagie (22.22%), autumnalis (20.35) and Bataviae (16.68%). While at the house mouse (R. tanezumi)­can­be­identified­serovar­autumnalis­(66.67%­of­3­tail)­and­Bataviae­(33.33%).­This­showsthat rats are an important reservoir of leptospirosis. This study shows that rats (R. norvegicus) and mice (R. tanezumi) has great potential to be a vector of transmission of the bacteria Leptospira in Semarang.

Keyword : Leptospirosis, Rats, Risk Factor, Semarang


Keywords


Leptospirosis, Rats, Risk Factor, Semarang

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P-ISSN : 2085-868X

EISSN  : 2354 - 8789

Published by Balai Besar Penelitian dan Pengembangan Vektor dan Reservoir Penyakit Salatiga

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Jurnal Kefarmasian Indonesia


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p-ISSN: 2085-675X

e-ISSN: 2354-8770

Jurnal Kefarmasian Indonesia is a scientific journal published by the Center for Research and Development of Biomedical and Basic Health Technology, Board of Health Research and Development, Ministry of Health of the Republic of Indonesia. The journal publishes original research articles in pharmaceutical science such as Pharmaceutical Technology, Pharmacology, Pharmaceutical Chemistry, Traditional Medicines, and Pharmaceutical Care.

The journal was established in 2009 while online publication has been started from 2015. The journal is published in Bahasa Indonesia and English.  Jurnal Kefarmasian Indonesia is biannual, open access, peer-reviewed, and online pharmacy journal. Jurnal Kefarmasian Indonesia aims to serve the updated scientific knowledge for researchers in pharmaceutical fields. There is no charge for submitted manuscript as well as for processing manuscript. The journal has been registered with e-ISSN 2354-8770, and p-ISSN 2085-675X and accredited by Indonesian Institute of Sciences (LIPI) with Decree No. 581/Akred/P2MI/LIPI/09/2014.

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EISSN: 2354 - 8770

Published by Center for Research and Development of Biomedical and Basic Health Technology

Jl. Percetakan Negara No. 23 Jakarta Pusat 10560

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