IMMUNOMODULATORY ACTIVITIY OF FRACTION EXTRACT FROM SWEET CORN SEEDS (Zea mays L.) ON MICE PERITONEAL

Kusmiati Kusmiati, Yudha Prasetya, Erlindha Ga

Abstract


Sweet corn (Zea mays L.) contains lutein that have potential as an immunomodulatory agent by improving immune system function. This study was aimed to determine the potential of sweet corn extract lutein as an immunomodulatory. Identification of luteinin the lutein fraction from sweet corn seed by TLC showed that the fraction contains lutein. This TLC data was confirmed using HPLC analysis. Identification of the functional group in the lutein extract using FTIR showed similar results with the lutein standard, i.e. there was a group C=C (Alkenyl), C-C (alkyl), -C=C (aromatic), and -OH (Hydroxyl). Immunomodulatory activity test was performed in vivousing mice peritoneal induced by Staphylococcus aureus. The luteinfraction with doses of 0.15, 0.3, 0.6, and 0.9 mg/kg BW/day.???? The results showed that the fraction were active as immunostimulant.


Keywords


Sweet corn (Zeamays L), lutein, immunomodulatory, phagocytosis, macrophage

References


REFERENCES

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Jurnal Tumbuhan Obat Indonesia (Journal of  Indonesian Medicinal Plant, p-ISSN : 1979-892X, e-ISSN : 2354-8797) is published by Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional (B2P2TOOT) Tawangmangu.

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