BIOAKTIVITAS ANTIDIABETES BEBERAPA JENIS POHON LOKAL DARI HUTAN KERANGAS (Andiabetic Bioactivity of some Local Trees Species from Kerangas Forest)

Kissinger Kissinger, Ahmad Yamani, Gusti AR Thamrin, Rina Muhayah NP, Ervizal AM Zuhud

Abstract


Bioactivity evaluation of trees species is an important step to get high economic value from Kerangas forest. Screening of plants that had antidiabetic activities was conducted by ethnobotanical survey. Antidiabetic evaluation of plant extracts were performed by α glukosidase inhibitor. Result showed there are three plant exracts from Kerangas forest had anti diabetic activity. The methanol extract of dried bark of Shorea balangeran, Cratoxylum arborescens and Baeckea frutescens inhibited 50% of α glukosidase activity at concentration: 0,816 ppm, 5,234 ppm, 21,796 ppm, respectively, while the IC50 of glukobay: 0,167 ppm. It can be conclude that methanol extract of Kerangas plant species had potential activities as antidiabetic.


Keywords


α-glukosidase, antidiabetic, kerangas forest

References


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Jurnal Tumbuhan Obat Indonesia (Journal of  Indonesian Medicinal Plant, p-ISSN : 1979-892X, e-ISSN : 2354-8797) is published by Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional (B2P2TOOT) Tawangmangu.

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