Efek Anti Ulkus Eurycoma longifolia terhadap Ulkus Lambung Tikus

Yovita Gunawan, Sjarif Ismail

Efek Anti Ulkus Eurycoma longifolia terhadap Ulkus Lambung Tikus

Abstract


Eurycoma longifolia (pasak bumi) are widely found in East Kalimantan. Etnobotanically, the roots of this plant were used to decrease gastric pain and anti ulcers, but scientific evidences have not been available yet. The objective of this research was to test the anti-ulcer effect of Eurycoma longifolia against gas­ tric ulcers in rats. Water extract of Eurycoma longifolia's root was given to the rats before induced gastric ulcer. The rats were induced gastric ulcer by giving acetyl salicylic acid orally and pyloric-ligation. The result showed that water extract of Eurycoma longifolia's root could prevent from increase of gastric ulcer index and decrease of gastric mucosa in rats induced gastric ulcer by acetyl salicylic acid, prevent from increase of free gastric acid in rats pyloric ligated. This research concluded that water extract of Eurycoma longifolia has anti-ulcer effect against gastric ulcers in rats induced by acetyl salicylic acid and pyloric­ ligation.

 

Key Word: Eurycoma longifolia, antiulcer, gastriculcer


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Jurnal Tumbuhan Obat Indonesia (Journal of  Indonesian Medicinal Plant, p-ISSN : 1979-892X, e-ISSN : 2354-8797) is published by Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional (B2P2TOOT) Tawangmangu.

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