PENGARUH JENIS KONTRASEPSI TERHADAP STATUS IODIUM WANITA USIA SUBUR (WUS) SETELAH PEMBERIAN KAPSUL BERIODIUM DI KECAMATAN ENDEMIK GAKI

Asih Setyani, Donny K. M., Suryati K.

PENGARUH JENIS KONTRASEPSI TERHADAP STATUS IODIUM WANITA USIA SUBUR (WUS) SETELAH PEMBERIAN KAPSUL BERIODIUM DI KECAMATAN ENDEMIK GAKI

Abstract


Background: Type of contraception that contain estrogen in IDD endemic area may aggravate hypothyroid. Contraceptive methods are divided into hormonal  contraceptives (pills, injections and implants) and non-hormonal.

Objectives: To determine the impact of contraceptives to iodine status of childbearing age women after iodine supplementation in endemic area. The study was conducted Kajoran health center of Magelang district of central Java. Research conducted during May to December 2006.

Methods: Research design pre and post test design. Population study of childbearing age women (CBAW) aged 18 to 45 years. Research subjects of hormonal contraception (35 people) and as a comparison subject is non hormonal contraception (35 people). Data collection was conducted before and after supplementation of iodine capsules (200 mg). Each subject received two capsules and was evaluated three days and six months later. Data collected were serum TSH and urine iodine excretion. Processing and data analysis done by computer. To see the influence of contraception to iodine status used paired T-test.

Results: The baseline data showed that no significant difference in the TSH and UIE between CBAW with hormonal contraception and non hormonal contraception. After three days intervention the UIE of both groups increased significantly 2115,00 µg/L (1775-2400) and 2114,00(µg/L) (1260-2460). After six month intervention the UIE of both group still considered high, 391,00(µg/L) (5,00-603,0) and 357,00(µg/L) (37,00-611,0) and significant difference, the TSH of both group decreased 1,63(0,81-9,29) and 1,85(0,7-11,14) but no significant difference.

Conclusion: The impact of contraceptives after iodine supplementation in research area not cause difference significant to iodine status ofboth group.

Keywords: contraceptives,iodine supplementation, iodine status, childbearing age women


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Media Gizi Mikro Indonesia (Indonesian Journal of Micronutrient, p-ISSN: 2086-5198, e-ISSN: 2354-8746) is published by Balai Penelitian dan Pengembangan Gangguan Akibat Kekurangan Iodium (Balai Litbang GAKI), Badan Penelitian dan Pengembangan Kesehatan, Ministry of Health of Republic of Indonesia.

Kapling Jayan, Kec. Borobudur, Kabupaten Magelang

http://ejournal.litbang.depkes.go.id/index.php/mgmi

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