Effect of fever duration before hospitalization and hemoconcentration to length of stay of dengue patients

Christine Ernita Banggai

Abstract


Abstrak

Latar Belakang: Identifikasi dini kondisi klinis serta penanganan yang tepat terhadap pasien dengue merupakan hal penting untuk mencegah perkembangan penyakit menjadi lebih berat. Hal ini akan berdampak positif bagi perawatan pasien yang menjadi lebih singkat dan dengan sendirinya biaya semakin rendah. Tujuan kajian adalah untuk mengetahui pengaruh durasi demam sebelum pasien dirawat di rumah sakit dan hemokonsentrasi terhadap lama waktu perawatan pasien dengue.

Metode: Studi potong lintang secara random sampling yang dilakukan terhadap catatan medis pasien dengue yang dirawat inap di RSPI Prof. Dr. Sulianti Saroso periode Januari 2014 s/d Desember 2015. Analisis dilakukan secara multivariat dengan regresi Cox.

Hasil: Pada 153 sampel catatan medis pasien dengue yang dianalisis, hasil menunjukkan terdapat 21,6% pasien yang dirawat lebih dari 6 hari. Durasi demam sebelum pasien dirawat di rumah sakit dan hemokonsentrasi merupakan dua faktor  yang berpengaruh signifikan terhadap lama perawatan pasien lebih dari 6 hari. Subyek dengan durasi demam 3 hari [aRR=0.38; P=0.024]  dan lebih dari 3 hari sebelum dirawat di rumah sakit [aRR=0.27; P=0.000] berpengaruh signifikan terhadap lama perawatan lebih dari 6 hari. Subyek dengan hemokonsentrasi menunjukkan risiko 1,8 kali lebih besar untuk lama perawatan lebih dari 6  hari [aRR=1.84; P=0.042].

Kesimpulan: Durasi demam 3 hari dan lebih dari 3 hari sebelum dirawat di rumah sakit serta adanya hemokonsentrasi pada pasien dengue di RSPI Prof. Dr. Sulianti Saroso, berperan signifikan terhadap lama waktu perawatan lebih dari 6  hari.

Kata kunci: Dengue, durasi demam, hemokonsentrasi, lama perawatan

 

Abstract

Backgrounds: Early identification of clinical conditions and proper treatment to dengue patients is essential to prevent the development of more severe condition. This can lead to shorter length of stay and lower cost of patient care in hospitals. The objective of this study was to determine the effect of fever duration before hospitalization and hemoconcentration to length of stay of dengue patients.

 

Methods: A cross-sectional study conducted by random sampling on the medical records of dengue patients hospitalized in RSPI Prof. Dr. Sulianti Saroso period January 2014-December 2015. Multivariate analyzes were performed with Cox regression.

 

Results: There were 153 samples of dengue patient’s medical record for analysis, 21.6% of them were hospitalized over 6 days. Duration of fever before hospitalization and hemoconcentration were significant to length of stay more than 6 days. Subjects with duration of fever for 3 days [aRR = 0.38; P = 0.024] and more than 3 days before hospitalization [aRR = 0.27; P = 0.000] were significant to length of stay more than 6 days. Subjects with hemoconcentration had higher risk  by 1,8 times to length of stay more than 6 days  [aRR = 1.84; P = 0.042].

Conclusion: Fever duration for 3 days, for more than 3 days before hospitalization, and hemoconcentration in dengue patients were significantly related to length of stay more than 6 days.

 

Keywords: Dengue, fever duration, hemoconcentration, length of stay

 

 

 


Keywords


Dengue, fever duration, hemoconcentration, length of stay

References


World Health Organization. Comprehensive guidelines for prevention and control of dengue and dengue hemorrhagic fever. India: WHO Regional Office for South East Asia. 2011

Ministry of Health of the Republic of Indonesia. Health profile of Indonesia year 2014. Jakarta. 2015.

Ministry of Health of the Republic of Indonesia. Health profile of Indonesia year 2015. Jakarta. 2016.

Sulianti Saroso Infectious Disease Hospital. Annual report. Jakarta. 2015

Widijanti A, Finfar V. Comparison of laboratory profiles between primary and secondary dengue. Medika Jurnal Kedokteran Indonesia. 2010; ISSN 0216-0910 No.01, Year XXXVI:12-7.

Ministry of Health of the Republic of Indonesia. Basic health research 2013. Jakarta: Balitbangkes. 2013:79

Nadeem Saqib MA, Rafique I, Bashir S, Salam AA. A retrospective analysis of dengue fever case management and frequency of co-morbidities associated with deaths. BMC Res Notes. 2014; 7:205

Ministry of Health of the Republic of Indonesia. Guidelines for control of dengue hemorrhagic fever in Indonesia. Jakarta. 2013.

Sumakto, Santoso NB, Nugroho S, Kawurjan SL. Hematocrit increased risk for the occurrence of seizures in cases of dengue hemorrhagic fever. Jurnal Kedokteran Brawijaya. Agustus 2004; XX(2):62-5

Pooransingh S, Teelucksingh S, Dialsingh I. Dengue deaths: associated factors and length of hospital stay. Adv Prev Med. 2016; 2016:6807674. doi: 1155/2016/6807674.

Kusumaningtyas A, Hapsari, Satoto B. Correlation between pleural effusion index and interpleura distance by ultrasonography in children with dengue hemorrhagic fever. Sari Pediatri. February 2015; 16(5): 339

Rasyada A, Nasrul E, Edward Z. Correlation between hematocrit count and platelet count in patients with dengue hemorrhagic fever. Jurnal Kesehatan Andalas. 2014; 3(3)

Mallhi TH, Khan AH, Adnan AS, Sarriff A, Khan YH, Jummat F. Incidence, characteristics and risk factors of acute kidney injury among dengue patients: A retrospective analysis. PLoS One. 2015 Sep 30; 10(9):e0138465. doi: 1371/journal.pone.0138465

Khalil MAM, Tan J, Khalil MAU, Awan S, Rangasami M. Predictors of hospital stay and mortality in dengue virus infection-experience from Aga Khan University Hospital Pakistan. BMC Res Notes. 2014; 7:473.

Basuki B. Multivariate analysis, linear regression-logistics-cox: core application for the stata program. Medical Faculty of University of Indonesia. 2010.


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